EFFECT OF PINEAPPLE (ANANAS COMOSUS) AND UZIZA (PIPER GUINEENSE) EXTRACTS ON FEXOFENADINE BIOAVAILABILITY: POSSIBLE ROLE OF P-GLYCOPROTEIN (P-GP) AND ORGANIC ANION TRANSPORTING POLYPEPTIDES (OATPS)
نویسندگان
چکیده
منابع مشابه
Role of organic anion transporting polypeptides (OATPs) for cellular mesalazine (5-aminosalicylic acid) uptake
Institute of Experimental and Clinical Pharmacology and Toxicology, University of Erlangen-Nuremberg, Fahrstr. 17, 91054 Erlangen, Germany (J.K., H.G., K.M., M.F.F.) Department of Pharmacology, Research Center of Pharmacology and Experimental Therapeutics, Ernst-Moritz-Arndt-University, 17487 Greifswald, Germany (M.K.) Dr. Margarete Fischer-Bosch-Institute of Clinical Pharmacology, 70376 Stuttg...
متن کاملOrganic anion-transporting polypeptides.
Organic anion-transporting polypeptides or OATPs are central transporters in the disposition of drugs and other xenobiotics. In addition, they mediate transport of a wide variety of endogenous substrates. The critical role of OATPs in drug disposition has spurred research both in academia and in the pharmaceutical industry. Translational aspects with clinical questions are the focus in academia...
متن کاملTissue distribution and ontogeny of mouse organic anion transporting polypeptides (Oatps) Department of Pharmacology, Toxicolo
Organic anion transporting polypeptides (Oatps) are Na-independent solute carriers for cellular uptake of organic compounds. The purpose of this study is to determine: 1) the constitutive mRNA expression of the 15 mouse Oatp genes in 12 tissues, 2) whether there are gender differences in Oatp expression, and 3) the ontogenic expression of Oatps in liver and kidney. The mRNA expression of the 15...
متن کاملTissue distribution and ontogeny of mouse organic anion transporting polypeptides (Oatps).
Organic anion-transporting polypeptides (Oatps) are Na(+)-independent solute carriers for cellular uptake of organic compounds. The purpose of this study is to determine 1) the constitutive mRNA expression of the 15 mouse Oatp genes in 12 tissues, 2) whether there are gender differences in Oatp expression, and 3) the ontogenic expression of Oatps in liver and kidney. The mRNA expression of the ...
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ژورنال
عنوان ژورنال: International Research Journal Of Pharmacy
سال: 2018
ISSN: 2230-8407
DOI: 10.7897/2230-8407.09337